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       Francisco J. Romero Campero

          Research Fellow Juan de la Cierva
         Group on Natural Computing                                                            
         Higher Technical School of Computer Engineering
         Faculty of Mathematics

         University of Seville  

      


 
I have contributed to the development of the following software:

  • Infobiotics Workbench is a computational framework implementing a synergy between executable biology, multi-compartmental stochastic simulations, formal model analysis and structural/parameter model optimisation for computational systems and synthetic biology. It provides a user-friendly front-end allowing the modeller to design in-silico experiments, analyse and visualise results using its four components:
    • A modelling language based on P systems which allows modular and parsimonious multi-cellular model development including geometric information.
    • A multi-compartmental stochastic simulator based on Gillespie’s Stochastic Simulation Algorithm for multi-cellular systems.
    • Formal model analysis using the stochastic model checkers PRISM and MC2 for the study of temporal and spatial model properties.
    • Structural and parameter model optimisation using evolutionary algorithms to automatically generate models whose dynamics match specified targets.