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Research
Fellow Juan de la Cierva
Group on Natural Computing
Higher Technical School of Computer Engineering
Faculty of Mathematics
University of Seville
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I have contributed to the
development of the following software:
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Infobiotics Workbench is a computational framework implementing a
synergy between executable biology, multi-compartmental stochastic
simulations, formal model analysis and structural/parameter model
optimisation for computational systems and synthetic biology. It provides
a user-friendly front-end allowing the modeller to design in-silico
experiments, analyse and visualise results using its four components:
- A modelling language based on P systems which allows modular and
parsimonious multi-cellular model development including geometric
information.
- A multi-compartmental stochastic simulator based on Gillespie’s
Stochastic Simulation Algorithm for multi-cellular systems.
- Formal model analysis using the stochastic model checkers PRISM and
MC2 for the study of temporal and spatial model properties.
- Structural and parameter model optimisation using evolutionary
algorithms to automatically generate models whose dynamics match
specified targets.
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